Cephalotaxus harringtonia is an evergreen coniferous shrub native to Japan, Korea, and China. It is one of the few conifers that performs reliably in deep shade, making it a practical choice for understory planting, north-facing foundations, and dry-shade problem areas where most evergreens fail. Deer largely avoid it, and it functions as a useful substitute for Taxus in zones where yew suffers from summer heat.
Growth is slow. The species can eventually reach small-tree size in ideal conditions, but most garden cultivars stay within 3–10 ft. 'Fastigiata' forms a dense upright column; 'Prostrata' and 'Duke Gardens' spread low and wide. All tolerate clay soils better than most conifers and become reasonably drought tolerant once established. Mulching the root zone conserves moisture and moderates soil temperature, which is especially important at the warm end of the hardiness range. Slightly acidic soil is preferred, though the plant adapts to a wider pH range than many broadleaf evergreens.
The bark and foliage contain cephalotaxine alkaloids, including homoharringtonine. Omacetaxine mepesuccinate, derived from this compound, received FDA approval in 2012 as a treatment for chronic myeloid leukemia resistant to tyrosine kinase inhibitors.
Root rot
Plants wilt, yellow, and stunt even in moist soil; lower stems and roots turn brown, soft, and mushy and the plant may collapse. Most common in heavy, wet, or poorly drained ground.
Improve drainage and stop overwatering, and never plant too deep. Lift and destroy badly affected plants along with the soil around the roots. Grow in raised or free-draining beds to prevent it returning.
Phytophthora Root Rot
Wilting despite moist soil, yellowing leaves, stunted growth, and dark, decayed roots and crown tissue. Vines may collapse during hot weather.
Plant in well-draining soil and avoid waterlogging. Remove and destroy affected vines. Improve drainage with raised beds or amended soil and avoid overwatering.